Sunday, July 20, 2014

Osteogenesis Imperfecta



Osteogenesis Imperfecta also known as "brittle bone disease" is a genetic disorder due to defective synthesis of type I collagen with generalized involvement of the bones, teeth, ligaments, sclerae and skin. Clinical features include propensity to fracture, generally after minor trauma, the skin is thin and somewhat loose and the joints are hypermobile. These patients can also present grey or blue sclera and crumbling teeth (dentinogenesis imperfecta). Here we have a sample of the blue sclera in this patient.
 

Saturday, July 19, 2014

Erythroblastosis Fetalis





Erythroblastosis Fetalis due to maternal–fetal Rh incompatibility. (Pathogenesis)

Immunization of an Rh-negative mother with Rh-positive erythrocytes in the first pregnancy leads to formation of anti-Rh antibodies of the immunoglobulin (Ig) G type. These antibodies cross the placenta and damage the Rh-positive fetus in subsequent pregnancies.


Friday, January 24, 2014

2º AV Block Mobitz Type I


Nice ilustration of second degree AV Block Mobitz type I (Wenckebach) showing the progressive PR segment prolongation until a beat is dropped due to failure of the AV node to conduct the impulse. Then the cycle is reset again given the same pattern prolonged, prolonged, prolonged, dropped.

Source: Compound Fracture, medcomic.

Wednesday, January 15, 2014